Effect of Carbamate Insecticide, Lannate, on the Gonads of Mice


  • A. M. T. Saleh Biology Department, Faculty of Applied Sciences, Umm Al-Qura University, Makka, 21955, PO Box 715, Kingdom of Saudi Arabia.
  • A. M. Hijji Biology Department, Faculty of Applied Sciences, Umm Al-Qura University, Makka, 21955, PO Box 715, Kingdom of Saudi Arabia.
  • S. J. Elel Biology Department, Faculty of Applied Sciences, Umm Al-Qura University, Makka, 21955, PO Box 715, Kingdom of Saudi Arabia.
  • A. N. Al Yacoub Biology Department, Faculty of Applied Sciences, Umm Al-Qura University, Makka, 21955, PO Box 715, Kingdom of Saudi Arabia.


Testis, Ovary, Histological examination, Seminiferous tubules, Ovarian follicles, Corpora lutea


The effect of the carbamate insecticide, lannate, on the gonads of mice was studied. Treating mice with lannate at a dose level of 10mg/kg body weight daily for 3-6 weeks had induced degenerative effects in the gonads, as follows, first in testis, a significant reduction in the diameter of the seminiferous tubules and germinal epithelial height. Histological examination of the testis showed that the seminiferous tubules were elongated and contained reduced spermatogenic cells. The number, of mature sperms was markedly reduced and after 3 weeks the sperm bundles were completely absent. On the other hand, the effect on the ovarian structure showed that, decrease in the number of secondary ovarian follicles and corpora lutea was recorded, while, the number of atretic follicles showed a significant increase. It is speculated that it may be resulted from the inhibition of RNA synthesis due to the effect of lannate.


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How to Cite

Saleh, A. M. T., Hijji, A. M., Elel, S. J., & Al Yacoub, A. N. (2014). Effect of Carbamate Insecticide, Lannate, on the Gonads of Mice. Journal of Advanced Laboratory Research in Biology, 5(4), 140–145. Retrieved from https://e-journal.sospublication.co.in/index.php/jalrb/article/view/208