Syzygium cumini Leaf Extract Showed Vibriocidal Activity on Selected Diarrhea Causing Bacteria

Authors

  • Nilanjana Paul Department of Genetic Engineering and Biotechnology, University of Dhaka, Dhaka-1000, Bangladesh.
  • Anwarul A. Akhand Department of Genetic Engineering and Biotechnology, University of Dhaka, Dhaka-1000, Bangladesh.
  • Sahab Uddin Babu Department of Genetic Engineering and Biotechnology, University of Dhaka, Dhaka-1000, Bangladesh.
  • Nazrul Islam Laboratory Science Division, ICDDR, B, Mohakhali, Dhaka-1212, Bangladesh.
  • Nazmul Ahsan Department of Genetic Engineering and Biotechnology, University of Dhaka, Dhaka-1000, Bangladesh.

Keywords:

Plant extract, Vibrio, Cholera, Vibriocidal activity

Abstract

The objective of the study was to investigate the effect of ethanolic leaf extract (ELE) of Syzygium cumini against Vibrio cholerae particularly two serogroups Ogawa and Inaba. The phenolic content of the ELE was found high which is comparable to ascorbic acid. Brine shrimp lethality bioassay was then performed to check the cytotoxic effects of ELE. The lower LC50 value of ELE obtained indicated its less cytotoxic properties. The antimicrobial activity of the extract was then evaluated by the disc diffusion method against multi-drug resistant Vibrio serogroups Ogawa and Inaba. The extract effectively inhibited the growth of both serogroups. Altogether, the results demonstrated that the ELE of S. cumini has a significant vibriocidal activity that might be useful as a drug for the treatment of cholera.

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References

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Published

03-07-2011

How to Cite

Paul, N., Akhand, A. A., Babu, S. U., Islam, N., & Ahsan, N. (2011). Syzygium cumini Leaf Extract Showed Vibriocidal Activity on Selected Diarrhea Causing Bacteria. Journal of Advanced Laboratory Research in Biology, 2(3), 108–111. Retrieved from https://e-journal.sospublication.co.in/index.php/jalrb/article/view/71

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