Effect of Adhatoda vasica (L.) Nees Leaf Extract Prepared by two Different Methods on Mitosis of Root Meristematic Cells of Allium cepa L.


  • Dimpy Das Borooah Centre for Studies in Biotechnology, Dibrugarh University-786 004, Assam, India.


Adhatoda vasica, Leaf Extract, Allium cepa, Genotoxicity, Cytotoxicity


Adhatoda vasica is a well-known plant drug in Ayurvedic and Unani medicine. Adhatoda leaves have been used extensively in Ayurvedic Medicine primarily for respiratory disorders. Aqueous leaf extract of A. vasica  was used to investigate its cytotoxic and genotoxic effects on root meristematic cells of Allium cepa. 1, 2.5, 5, 10 and 20% concentrations of leaf extract prepared by two different ways were used in the present study. It was found that leaf extract of  A. vasica exhibits mitodepressive activity as well as it induces disorder of chromosome kinetic including formation of sticky chromosome, c-metaphase, metaphasic and anaphasic disorders in Allium cepa root meristem.


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How to Cite

Borooah, D. D. (2011). Effect of Adhatoda vasica (L.) Nees Leaf Extract Prepared by two Different Methods on Mitosis of Root Meristematic Cells of Allium cepa L. Journal of Advanced Laboratory Research in Biology, 2(4), 141–145. Retrieved from https://e-journal.sospublication.co.in/index.php/jalrb/article/view/78