Journal of Advanced Laboratory Research in Biology Journal of Advanced Laboratory Research in Biology is a UGC Approved, Open access, Peer-reviewed, Biological Science Journal, published quarterly (January, April, July and October) by the Society of Open Science. Society of Open Science en-US Journal of Advanced Laboratory Research in Biology 0976-7614 The Integration of Microbial Inoculation and Organic Fertilization to Improve the Productivity of Wheat (Triticum aestivum L.) in New Land <p>This study was conducted to investigate the integration between the microbial inoculation and organic fertilization to improve the wheat productivity. Therefore, two wheat varieties (Misr-1 and Seds-12) were tested under three rates (8, 10 and 12 tons/fed) of supported compost and various microbial inoculation treatments during of 2012/2013 and 2013/2014 seasons. The main obtained results revealed that the Misr-1 wheat variety recorded significant increases in yield and its components except average of grains number/spike during the two seasons. Moreover, the interaction among three experiment factors showed that Misr-1 wheat variety, 10 ton/fed of supported compost and microbial inoculation by <em>Trichoderma + Bacillus subtilis</em> gave the greatest values for number of spike/m<sup>2</sup>, spike weight, average grain weight per spike, 1000-grain weight, biological yield, total yield/fed and protein content. However, highest number of grains per spike were recorded with Seds-12 wheat variety and 10 tons/fed of supported compost + inoculated by <em>Trichoderma + Bacillus subtilis</em>.</p> Mostafa AS AbdElgalil Osama MS Harb Abd El-Rahim S Abo-Elhamd Mustafa M Ibrahim Atef A Hassan ##submission.copyrightStatement## 2016-07-01 2016-07-01 7 3 66 75 Cuticular Biochemistry: Lambda-Cyhalothrin Induced Alterations in Mutant Drosophila melanogaster <p>Derivatives of natural pyrethrum, synthetic pyrethroids, are well-established neurotoxins. However, they do interfere with the functioning of metabolic processes; the most important of these is chitin metabolism, a key process in the development of insects. Type II synthetic pyrethroid, lambda-cyhalothrin, when orally fed to <em>Drosophila melanogaster</em> revealed its efficacy in chitin synthesis modulation. Total proteins, glucosamine, N-acetylglucosamine, chitinase activity and chitin content exhibit significant changes in the final developmental stage, the adults. A reduction in chitin synthesis is suggestive of interference in polymerization process which is a must for cuticle formation. Involvement of lambda-cyhalothrin in chitin synthesis has been sought to be an additional mode of action, other than its neurotoxic nature.</p> Harendra N. Sharma Prabhu N. Saxena Vishnu Kumar Upadhyay Namrata Rana Nishi Saxena ##submission.copyrightStatement## 2016-07-01 2016-07-01 7 3 76 78