Journal of Advanced Laboratory Research in Biology <p>Journal of Advanced Laboratory Research in Biology (ISSN: 0976-7614; CODEN: JALRC5) is an international, open access, peer-reviewed scholarly journal in the area of biological sciences and published quarterly by Society of Open Science.</p> Society of Open Science en-US Journal of Advanced Laboratory Research in Biology 0976-7614 <p><a href="" rel="license">Creative Commons Attribution 4.0 International License</a>.</p> Diagnosis and Differentiation of Hypochromic Microcytic Anemia among Elementary School Children in Ranya District <p>Hypochromic microcytic anemia (HMA) is defined as decreased hemoglobin (Hb), mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) levels, the most common causes of microcytic anemia in children are iron deficiency anemia (IDA) and thalassemia trait (TT). The cross-sectional study was conducted to diagnose and differentiate HMA among elementary school children in the Ranya district. A total of 134 subjects were included in the study of which 28 participants were healthy, and 106 subjects were diagnosed with HMA. The study subjects were divided into three groups. Group 1 with 28 healthy subjects, Group 2 with 38 IDA patients and Group 3 with 68 TT patients. Complete blood count, iron status (ferritin, serum iron, UIBC, TSAT (%) and TIBC), T3, T4, TSH, Erythropoietin hormone, Creatinine and GFR were estimated in all three groups. The results demonstrated that there was a significant decrease (<em>P </em>&lt; 0.0001) in Hb, HCT, MCV, MCH and MCHC in both IDA and TT patients. While significant increase was seen in RDW and PLT count in both IDA and TT. The result revealed a significant decrease (<em>P</em> &lt; 0.0001) in serum ferritin, serum iron and TSAT (%), whereas a significant increase in TIBC and UIBC in IDA. Serum erythropoietin (EPO) was increased significantly in both IDA and TT. Thyroid hormones (T3 and T4), TSH, serum creatinine and GFR were non-significantly changed in both IDA and TT patients.</p> Abdullah Watman Mohammed Zrar Saleem Kareem Copyright (c) 2021 Abdullah Watman Mohammed & Zrar Saleem Kareem 2021-02-15 2021-02-15 12 1 1 9 Thyroid Diseases with Vitamin D Deficiency in Erbil city <p>Vitamin D is essential for the proper growth and development of a child and is associated with numerous public health issues. Our study aimed to examine the relationship between vitamin D deficiency and thyroid diseases. Vitamin D sufficiency is defined in terms of the serum level of the prohormone 25(OH)D which is 30 ng/mL. <em>Vitamin D</em> level less than of it is considered as vitamin D deficiency. A total of 100 subjects were included in the present study who visited the Central Laboratory in Erbil for health examination between the beginning of September to the beginning of December 2020. The findings of the present study show a high prevalence of vitamin D deficiency (79%) among Erbil population. There was a negative correlation between Vitamin D serum levels and TSH levels (r = - 0.154) with a positive correlation between vitamin D serum levels and FT3 levels (r = 0.168) and FT4 levels (r = 0.122). The results showed that patients with vitamin D deficiency suffered from hypothyroidism. Additionally, the positive significant correlation between thyroid hormones with vitamin D and that negative significant correlation with TSH levels, suggested that low vitamin D levels are significantly associated with the severity of hypothyroidism which encourages the advisability of vitamin D supplementation.</p> Aso Omar Muhammed Sherwan Qadir Gulstan Mudhafar Mokhtar Bnar Mudhafar Mokhtar Copyright (c) 2021 Aso Hemn Omar, Muhammed Sherwan Qadir, Gulstan Mudhafar Mokhtar & Bnar Mudhafar Mokhtar 2021-02-15 2021-02-15 12 1 10 13